Hairstyles, Hair Care & Fashion

Cure for Male Baldness (2)

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The scientists continued study and found that there is a receptor that triggers the molecule’s destructive effects and been working on a way to use this receptor to devise a treatment to allow men in the early stages of baldness to hold onto their hair. This would work by introducing a molecule that would act as a “decoy” and bind to the receptor, which would prevent the PGD2 molecule from being able to act on the receptor. Without the binding to create the triggering effects, the PGD2 can’t cause any damaging effect to the follicle and would allow the follicle to continue producing hair according to its growth cycle.
Researchers have a handful of treatments focusing on the receptors already in clinical trials, but there is an interesting twist. PGD2 is also responsible for asthmatic conditions. The PGD2 molecule causes a reaction in bronchial tissues that leads to the contractions that are experienced by asthmatics and can be so dangerous in many cases. One of the drugs currently being tested in clinical trials is ramatroban, and scientists are trying to find ways to convert the oral and inhalable versions of the drug in the asthma trials in to topical treatments for use in hair loss research.
It should be noted that there is no known relationship between asthma and male pattern baldness, and that the PGD2 works differently in the two areas of the body. The enzymes that create PGD2 in the scalp come from the brain, and the PGD2 in the lungs which causes asthmatic reactions is blood-born. When an asthmatic comes in contact with an allergen trigger, the production of PGD2 goes into overdrive, leads to inflammation of the bronchial tissues and causes the difficulty in breathing. There has been no evidence to link asthmatic reactions caused by the PGD2 creation triggered in asthmatics with any hair loss in those individuals.
Unfortunately, there are factors that are still uncertain. There is no timetable for testing and trials of possible treatments. There are the factors of dosage and safety issues to be considered – and approval to be obtained - before testing could be performed. There is also the question of whether or not the treatment would be merely a preventive. It may not work on men who have already lost their hair. Even so, there is a great deal of hope to be had in the news that has been revealed in this research.
Stacy - Master Cosmetologist
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